Analysis and Identification of an Intraocular Pressure Waveform

Certain ocular diseases such as glaucoma cause an increase in the internal pressure of the eye, damaging nerves. An implantable pressure sensor would give patients the ability to monitor their own intraocular pressure and then consult a physician if necessary. One device to do this has been developed using a microscopic Fabry-Perot interferometer with the plates implanted between the intraocular membranes, and Raman spectroscopy measurements taken to determine the distance between the plates and thus the pressure in the eye. However the signal produced is difficult for a machine to recognize and link to the pressure environment of the sensor. To analyze the signals and convert their differences into numerical quantities, various signal processing techniques were investigated, such as using Fourier transforms, polynomial fit, and simple peak matching. A program combining these techniques to compare frequency shift across pressures and angles is currently being tested for consistency over samples at the same pressure.